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AIDS is a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive.Without treatment, average survival time after infection with HIV is estimated to be 9 to 11 years, depending on the HIV subtype.

Within these bodily fluids, HIV is present as both free virus particles and virus within infected immune cells.HIV-1 is the virus that was initially discovered and termed both LAV and HTLV-III.It is more virulent, more infective, and is the cause of the majority of HIV infections globally.Over half of the mass of the trimeric envelope spike is N-linked glycans.The density is high as the glycans shield the underlying viral protein from neutralisation by antibodies.

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